2010 – StudyCannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo.

2010 – StudyCannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy.

2010 – StudyAAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity.

2010 – StudyDelta-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.

2010 – StudyAnticonvulsant effects of GWP42006 in vitro and in vivo in rat.

2010 – StudyDynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans.

2011 – StudyEndocannabinoid system protects against cryptogenic seizures.

2011 – StudyConvulsions Associated with the Use of a Synthetic Cannabinoid Product.

2011 – StudyPro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy.

2011 – StudySynthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.

2011 – StudyProtective effects of CB1 receptor agonist WIN 55.212-2 in seizure activity in the model of temporal lobe epilepsy.

2011 – StudyL-Type Calcium Channel Mediates Anticonvulsant Effect of Cannabinoids in Acute and Chronic Murine Models of Seizure.

2011 – StudyChanges in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures.

2011 – StudyMarijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention.

2012 – Patent ApplicationUse of the phytocannabinoid cannabidivarin (cbdv) in the treatment of epilepsy: Patent Application 20120004251

2012 – StudyInverse relationship of cannabimimetic (R+)WIN 55, 212 on behavior and seizure threshold during the juvenile period.

2012 – StudyEquipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase – Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology.

2012 – StudyEpileptiform activity in the CA1 region of the hippocampus becomes refractory to attenuation by cannabinoids in part because of endogenous γ-aminobutyric acid type B receptor activity.

2012 – StudyCannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

2012 – StudyStatistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.

2012 – StudyCannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.

2012 – StudyInternet Highs-Seizures After Consumption of Synthetic Cannabinoids Purchased Online.

2012 – StudyCannabinoid receptor 1 inhibition causes seizures during anesthesia induction in experimental sepsis.

2012 – StudyEffect of ACEA-a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.

2013 – StudyAlterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder.

2013 – StudyCannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression

2013 – Study (article) ~ Medical Marijuana Coverage Still Lost in the Legal Weeds

2013 – StudyReport of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment- resistant epilepsy

2013 – StudyCannabis and other illicit drug use in epilepsy patients.

2013 – StudyThe Role of CB1-Receptors in the Proconvulsant Effect of Leptin on Penicillin-Induced Epileptiform Activity in Rats.

2013 – StudyThe role of potassium BK channels in anticonvulsant effect of cannabidiol in
pentylenetetrazole and maximal electroshock models of seizure in mice.

2013 – StudyCannabinoid 1 receptor as therapeutic target in preventing chronic epilepsy

2013 – StudyThe du2J mouse model of ataxia and absence epilepsy has deficient cannabinoid CB1 receptor-mediated signalling.

2013 – StudyThe role of α2-adrenoceptors in the anti-convulsant effects of cannabinoids on
pentylenetetrazole-induced seizure threshold in mice.

2013 – StudyCB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations.

2013 – StudyThe secret “spice”: an undetectable toxic cause of seizure.

2013 – StudyEffects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine,
oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures
in mice.

2013 – StudyTherapeutic potential of cannabinoid medicines.

2013 – StudyCannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism.

2013 – StudyEpidiolex – GW Pharmaceuticals (drug development page)

2013 – StudyFamilies migrate to Colorado for marijuana miracle

2013 – StudyComes Now Epidiolex (FDA approves IND studies of CBD

2013 – StudyPharmaceuticals Provides Update on Orphan Program in Childhood Epilepsy for
Epidiolex®

2013 – StudyEndogenous Signaling by Omega-3 Docosahexaenoic Acid-derived Mediators Sustains Homeostatic Synaptic and Circuitry Integrity.

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