1973 – Study ~ ANTI-EDEMA AND ANALGESIC PROPERTIES OF Δ9-TETRAHYDROCANNABINOL (THC).
2001 – Study ~ Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints.
2003 – Study ~ Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model.
2004 – Study ~ A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis.
2005 – Study ~ Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials.
2006 – Study ~ Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro.
2006 – Study ~ SAFETY AND TOLERABILITY OF LONG-TERM TREATMENT WITH A CANNABIS-BASED MEDICINE (SATIVEX) IN PATIENTS WITH RHEUMATOID ARTHRITIS.
2007 – Study ~ Arthritis and pain. Future targets to control osteoarthritis pain.
2007 – Study ~ INHIBITORY EFFECT OF CANNABINOID AGONISTS ON CYTOKINE PRODUCTION IN HUMAN OSTEOARTRITHIC AND RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTES.
2008 – Study ~ Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis.
2008 – Study ~ In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints.
2008 – Study ~ Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees.
2008 – Study ~ CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways.
2008 – Study ~ Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid.
2008 – Study ~ Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells.
2009 – Study ~ Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4.
2009 – Study ~ Cannabinoids as novel anti-inflammatory drugs.
2010 – Study ~ Tissue Engineering of Cartilage; Can Cannabinoids Help?
2010 – Study ~ Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression.
2010 – Study ~ Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain.
2010 – Study ~ Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis.
2010 – Study ~ Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain.
2011 – Study ~ Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials.
2011 – Study ~ Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.
2011 – Study ~ The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55.
2011 – Study ~ Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice.
2012 – Study ~ Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2.
2012 – Study ~ Effects of Peptide and Lipid Endocannabinoids on Arthritic Pain at Spinal Level.
2012 – Study ~ Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system.
2012 – Study ~ Cannabinoids: novel therapies for arthritis?