1. Impact of enzymatic and alkaline hydrolysis on CBD concentration in urine.
Bergamaschi MM, Barnes A, Queiroz RH, Hurd YL, Huestis MA.
Anal Bioanal Chem. 2013 Mar 15. [Epub ahead of print]
PMID: 23494274 [PubMed – as supplied by publisher]
Related citations


2. Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy.
Casarejos MJ, Perucho J, Gomez A, Muñoz MP, Fernandez-Estevez M, Sagredo O, Fernandez Ruiz J, Guzman M, de Yebenes JG, Mena MA.
J Alzheimers Dis. 2013 Mar 11. [Epub ahead of print]
PMID: 23478312 [PubMed – as supplied by publisher]
Related citations


3. Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses.
Sylantyev S, Jensen TP, Ross RA, Rusakov DA.
Proc Natl Acad Sci U S A. 2013 Mar 7. [Epub ahead of print]
PMID: 23472002 [PubMed – as supplied by publisher] Free Article
Related citations


4. Industrial hemp decreases intestinal motility stronger than indian hemp in mice.
Sabo A, Horvat O, Stilinovic N, Berenji J, Vukmirovic S.
Eur Rev Med Pharmacol Sci. 2013 Feb;17(4):486-90.
PMID: 23467947 [PubMed – in process]
Related citations


5. A GPR18-based signaling system regulates IOP in murine eye.
Caldwell MD, Hu SS, Viswanathan S, Bradshaw H, Kelly ME, Straiker A.
Br J Pharmacol. 2013 Mar 5. doi: 10.1111/bph.12136. [Epub ahead of print]
PMID: 23461720 [PubMed – as supplied by publisher]
Related citations


6. Cannabis, psychosis and the thalamus: Some new theoretical concepts and insights.
Vukadinovic Z, Herman MS, Rosenzweig I.
Neurosci Biobehav Rev. 2013 Feb 28. doi:pii: S0149-7634(13)00049-3. 10.1016/j.neubiorev.2013.02.013. [Epub ahead of print]
PMID: 23458778 [PubMed – as supplied by publisher]
Related citations


7. The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig.
Dudášová A, Keir SD, Parsons ME, Molleman A, Page CP.
Pulm Pharmacol Ther. 2013 Feb 18. doi:pii: S1094-5539(13)00059-X. 10.1016/j.pupt.2013.02.002. [Epub ahead of print]
PMID: 23428645 [PubMed – as supplied by publisher]
Related citations


8. [Marihuana and cannobinoids as medicaments].
Tkaczyk M, Florek E, Piekoszewski W.
Przegl Lek. 2012;69(10):1095-7. Polish.
PMID: 23421098 [PubMed – in process]
Related citations


9. Cannabis and Δ(9)-tetrahydrocannabinol (THC) for weight loss?
Le Foll B, Trigo JM, Sharkey KA, Strat YL.
Med Hypotheses. 2013 Feb 11. doi:pii: S0306-9877(13)00042-X. 10.1016/j.mehy.2013.01.019. [Epub ahead of print]
PMID: 23410498 [PubMed – as supplied by publisher]
Related citations


10. A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost-effectiveness in Germany.
Flachenecker P.
Expert Rev Neurother. 2013 Feb;13(3 Suppl 1):15-9. doi: 10.1586/ern.13.1.
PMID: 23369055 [PubMed – in process]
Related citations


11. Endocannabinoid system modulator use in everyday clinical practice in the UK and Spain.
García-Merino A.
Expert Rev Neurother. 2013 Feb;13(3 Suppl 1):9-13. doi: 10.1586/ern.13.4.
PMID: 23369054 [PubMed – in process]
Related citations


12. Development and validation of an LC-MS/MS method for quantification of Δ9-tetrahydrocannabinolic acid A (THCA-A), THC, CBN and CBD in hair.
Roth N, Moosmann B, Auwärter V.
J Mass Spectrom. 2013 Feb;48(2):227-33. doi: 10.1002/jms.3152.
PMID: 23378095 [PubMed – in process]
Related citations


13. Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.
Hernán Pérez de la Ossa D, Lorente M, Gil-Alegre ME, Torres S, García-Taboada E, Aberturas Mdel R, Molpeceres J, Velasco G, Torres-Suárez AI.
PLoS One. 2013;8(1):e54795. doi: 10.1371/journal.pone.0054795. Epub 2013 Jan 22.
PMID: 23349970 [PubMed – in process] Free PMC Article
Related citations


14. Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats.
Chagas MH, Crippa JA, Zuardi AW, Hallak JE, Machado-de-Sousa JP, Hirotsu C, Maia L, Tufik S, Andersen ML.
J Psychopharmacol. 2013 Mar;27(3):312-6. doi: 10.1177/0269881112474524. Epub 2013 Jan 23.
PMID: 23343597 [PubMed – in process]
Related citations


15. Cannabidiol is a Potent Inhibitor of the Catalytic Activity of Cytochrome P450 2C19.
Jiang R, Yamaori S, Okamoto Y, Yamamoto I, Watanabe K.
Drug Metab Pharmacokinet. 2013 Jan 15. [Epub ahead of print]
PMID: 23318708 [PubMed – as supplied by publisher] Free Article
Related citations


16. Cannabidiol enhances consolidation of explicit fear extinction in humans.
Das RK, Kamboj SK, Ramadas M, Yogan K, Gupta V, Redman E, Curran HV, Morgan CJ.
Psychopharmacology (Berl). 2013 Jan 10. [Epub ahead of print]
PMID: 23307069 [PubMed – as supplied by publisher]
Related citations


17. The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.
Campos AC, Ortega Z, Palazuelos J, Fogaça MV, Aguiar DC, Díaz-Alonso J, Ortega-Gutiérrez S, Vázquez-Villa H, Moreira FA, Guzmán M, Galve-Roperh I, Guimarães FS.
Int J Neuropsychopharmacol. 2013 Jan 9:1-13. [Epub ahead of print]
PMID: 23298518 [PubMed – as supplied by publisher]
Related citations


18. Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR.
Happyana N, Agnolet S, Muntendam R, Van Dam A, Schneider B, Kayser O.
Phytochemistry. 2013 Mar;87:51-9. doi: 10.1016/j.phytochem.2012.11.001. Epub 2012 Dec 29.
PMID: 23280038 [PubMed – in process]
Related citations


19. Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.
Maor Y, Yu J, Kuzontkoski PM, Dezube BJ, Zhang X, Groopman JE.
Genes Cancer. 2012 Jul;3(7-8):512-20. doi: 10.1177/1947601912466556.
PMID: 23264851 [PubMed] Free PMC Article
Related citations


20. Endocannabinoid system and mood disorders: Priming a target for new therapies.
Micale V, Di Marzo V, Sulcova A, Wotjak CT, Drago F.
Pharmacol Ther. 2013 Apr;138(1):18-37. doi: 10.1016/j.pharmthera.2012.12.002. Epub 2012 Dec 20.
PMID: 23261685 [PubMed – in process]
Related citations


21. Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.
Soroceanu L, Murase R, Limbad C, Singer E, Allison J, Adrados I, Kawamura R, Pakdel A, Fukuyo Y, Nguyen D, Khan S, Arauz R, Yount GL, Moore DH, Desprez PY, McAllister SD.
Cancer Res. 2013 Mar 1;73(5):1559-69. doi: 10.1158/0008-5472.CAN-12-1943. Epub 2012 Dec 13.
PMID: 23243024 [PubMed – in process]
Related citations


22. What place for ▾ cannabis extract in MS?
[No authors listed]
Drug Ther Bull. 2012 Dec;50(12):141-4. doi: 10.1136/dtb.2012.11.0150.
PMID: 23241565 [PubMed – in process]
Related citations


23. Involvement of UDP-Glucuronosyltransferases UGT1A9 and UGT2B7 in Ethanol Glucuronidation, and Interactions with Common Drugs of Abuse.
Al Saabi A, Allorge D, Sauvage FL, Tournel G, Gaulier JM, Marquet P, Picard N.
Drug Metab Dispos. 2013 Mar;41(3):568-74. doi: 10.1124/dmd.112.047878. Epub 2012 Dec 10.
PMID: 23230132 [PubMed – in process]
Related citations


24. COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.
Ramer R, Heinemann K, Merkord J, Rohde H, Salamon A, Linnebacher M, Hinz B.
Mol Cancer Ther. 2013 Jan;12(1):69-82. doi: 10.1158/1535-7163.MCT-12-0335. Epub 2012 Dec 7.
PMID: 23220503 [PubMed – in process]
Related citations


25. Angiotensin-2-mediated Ca2+ signaling in the retinal pigment epithelium: role of angiotensin-receptor-associated-protein and TRPV2 channel.
Barro-Soria R, Stindl J, Müller C, Foeckler R, Todorov V, Castrop H, Strauß O.
PLoS One. 2012;7(11):e49624. doi: 10.1371/journal.pone.0049624. Epub 2012 Nov 20.
PMID: 23185387 [PubMed – in process] Free PMC Article
Related citations


26. A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis.
Langford RM, Mares J, Novotna A, Vachova M, Novakova I, Notcutt W, Ratcliffe S.
J Neurol. 2012 Nov 21. [Epub ahead of print]
PMID: 23180178 [PubMed – as supplied by publisher]
Related citations


27. A phase I study to assess the single and multiple dose pharmacokinetics of THC/CBD oromucosal spray.
Stott CG, White L, Wright S, Wilbraham D, Guy GW.
Eur J Clin Pharmacol. 2012 Nov 22. [Epub ahead of print]
PMID: 23179176 [PubMed – as supplied by publisher]
Related citations


28. Cannabidiol (CBD) enhances lipopolysaccharide (LPS)-induced pulmonary inflammation in C57BL/6 mice.
Karmaus PW, Wagner JG, Harkema JR, Kaminski NE, Kaplan BL.
J Immunotoxicol. 2012 Nov 23. [Epub ahead of print]
PMID: 23173851 [PubMed – as supplied by publisher]
Related citations


29. Can oral fluid cannabinoid testing monitor medication compliance and/or cannabis smoking during oral THC and oromucosal Sativex administration?
Lee D, Karschner EL, Milman G, Barnes AJ, Goodwin RS, Huestis MA.
Drug Alcohol Depend. 2012 Nov 9. doi:pii: S0376-8716(12)00411-5. 10.1016/j.drugalcdep.2012.10.011. [Epub ahead of print]
PMID: 23146820 [PubMed – as supplied by publisher]
Related citations


30. An Open-Label Extension Study to Investigate the Long-Term Safety and Tolerability of THC/CBD Oromucosal Spray and Oromucosal THC Spray in Patients With Terminal Cancer-Related Pain Refractory to Strong Opioid Analgesics.
Johnson JR, Lossignol D, Burnell-Nugent M, Fallon MT.
J Pain Symptom Manage. 2012 Nov 7. doi:pii: S0885-3924(12)00439-3. 10.1016/j.jpainsymman.2012.07.014. [Epub ahead of print]
PMID: 23141881 [PubMed – as supplied by publisher]
Related citations


31. Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test.
Almeida V, Levin R, Peres FF, Niigaki ST, Calzavara MB, Zuardi AW, Hallak JE, Crippa JA, Abílio VC.
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Mar 5;41:30-5. doi: 10.1016/j.pnpbp.2012.10.024. Epub 2012 Nov 2.
PMID: 23127569 [PubMed – in process]
Related citations


32. Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A) receptor activation.
Bolognini D, Rock E, Cluny N, Cascio M, Limebeer C, Duncan M, Stott C, Javid F, Parker L, Pertwee R.
Br J Pharmacol. 2013 Mar;168(6):1456-1470. doi: 10.1111/bph.12043.
PMID: 23121618 [PubMed – as supplied by publisher]
Related citations


33. Medical use of cannabis. Cannabidiol: a new light for schizophrenia?
Deiana S.
Drug Test Anal. 2013 Jan;5(1):46-51. doi: 10.1002/dta.1425. Epub 2012 Oct 25.
PMID: 23109356 [PubMed – in process]
Related citations


34. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders.
Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS.
Philos Trans R Soc Lond B Biol Sci. 2012 Dec 5;367(1607):3364-78. doi: 10.1098/rstb.2011.0389.
PMID: 23108553 [PubMed – in process]
Related citations


35. Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities.
Pertwee RG.
Philos Trans R Soc Lond B Biol Sci. 2012 Dec 5;367(1607):3353-63. doi: 10.1098/rstb.2011.0381.
PMID: 23108552 [PubMed – in process]
Related citations


36. N-Arachidonyl glycine does not activate G protein-coupled receptor 18 signaling via canonical pathways.
Lu VB, Puhl HL 3rd, Ikeda SR.
Mol Pharmacol. 2013 Jan;83(1):267-82. doi: 10.1124/mol.112.081182. Epub 2012 Oct 25.
PMID: 23104136 [PubMed – in process]
Related citations


37. Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability.
O’Brien LD, Wills KL, Segsworth B, Dashney B, Rock EM, Limebeer CL, Parker LA.
Pharmacol Biochem Behav. 2013 Jan;103(3):597-602. doi: 10.1016/j.pbb.2012.10.008. Epub 2012 Oct 25.
PMID: 23103902 [PubMed – in process]
Related citations


38. Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report.
Crippa JA, Hallak JE, Machado-de-Sousa JP, Queiroz RH, Bergamaschi M, Chagas MH, Zuardi AW.
J Clin Pharm Ther. 2013 Apr;38(2):162-4. doi: 10.1111/jcpt.12018. Epub 2012 Oct 24.
PMID: 23095052 [PubMed – in process]
Related citations


39. Cannabidiol reduces host immune response and prevents cognitive impairments in Wistar rats submitted to pneumococcal meningitis.
Barichello T, Ceretta RA, Generoso JS, Moreira AP, Simões LR, Comim CM, Quevedo J, Vilela MC, Zuardi AW, Crippa JA, Teixeira AL.
Eur J Pharmacol. 2012 Dec 15;697(1-3):158-64. doi: 10.1016/j.ejphar.2012.09.053. Epub 2012 Oct 16.
PMID: 23085269 [PubMed – in process]
Related citations


40. Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.
Nabissi M, Morelli MB, Santoni M, Santoni G.
Carcinogenesis. 2013 Jan;34(1):48-57. doi: 10.1093/carcin/bgs328. Epub 2012 Oct 18.
PMID: 23079154 [PubMed – indexed for MEDLINE]
Related citations


41. A phase I study to assess the effect of food on the single dose bioavailability of the THC/CBD oromucosal spray.
Stott CG, White L, Wright S, Wilbraham D, Guy GW.
Eur J Clin Pharmacol. 2012 Oct 4. [Epub ahead of print]
PMID: 23052407 [PubMed – as supplied by publisher]
Related citations


42. Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment.
Englund A, Morrison PD, Nottage J, Hague D, Kane F, Bonaccorso S, Stone JM, Reichenberg A, Brenneisen R, Holt D, Feilding A, Walker L, Murray RM, Kapur S.
J Psychopharmacol. 2013 Jan;27(1):19-27. doi: 10.1177/0269881112460109. Epub 2012 Oct 5.
PMID: 23042808 [PubMed – in process]
Related citations


43. Cannabidiol administration into the bed nucleus of the stria terminalis alters cardiovascular responses induced by acute restraint stress through 5-HT(1A) receptor.
Gomes FV, Alves FH, Guimarães FS, Correa FM, Resstel LB, Crestani CC.
Eur Neuropsychopharmacol. 2012 Oct 4. doi:pii: S0924-977X(12)00271-4. 10.1016/j.euroneuro.2012.09.007. [Epub ahead of print]
PMID: 23041353 [PubMed – as supplied by publisher]
Related citations


44. [Treatment of spasticity in multiple sclerosis: new perspectives regarding the use of cannabinoids].
Oreja-Guevara C.
Rev Neurol. 2012 Oct 1;55(7):421-30. Spanish.
PMID: 23011861 [PubMed – in process] Free Article
Related citations


45. Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats.
Campos AC, de Paula Soares V, Carvalho MC, Ferreira FR, Vicente MA, Brandão ML, Zuardi AW, Zangrossi H Jr, Guimarães FS.
Psychopharmacology (Berl). 2013 Mar;226(1):13-24. doi: 10.1007/s00213-012-2878-7. Epub 2012 Sep 25.
PMID: 23007604 [PubMed – in process]
Related citations


46. Distribution of free and conjugated cannabinoids in human bile samples.
Fabritius M, Staub C, Mangin P, Giroud C.
Forensic Sci Int. 2012 Nov 30;223(1-3):114-8. doi: 10.1016/j.forsciint.2012.08.013. Epub 2012 Sep 11.
PMID: 22980143 [PubMed – in process]
Related citations


47. Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors.
Campos AC, Ferreira FR, Guimarães FS.
J Psychiatr Res. 2012 Nov;46(11):1501-10. doi: 10.1016/j.jpsychires.2012.08.012. Epub 2012 Sep 11.
PMID: 22979992 [PubMed – in process]
Related citations


48. Direct analysis of cannabis samples by desorption atmospheric pressure photoionization-mass spectrometry.
Kauppila TJ, Flink A, Laakkonen UM, Aalberg L, Ketola RA.
Drug Test Anal. 2013 Mar;5(3):186-90. doi: 10.1002/dta.1412. Epub 2012 Sep 13.
PMID: 22977002 [PubMed – in process]
Related citations


49. Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity.
Leussink VI, Husseini L, Warnke C, Broussalis E, Hartung HP, Kieseier BC.
Ther Adv Neurol Disord. 2012 Sep;5(5):255-66. doi: 10.1177/1756285612453972.
PMID: 22973422 [PubMed] Free PMC Article
Related citations


50. A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis.
Granja AG, Carrillo-Salinas F, Pagani A, Gómez-Cañas M, Negri R, Navarrete C, Mecha M, Mestre L, Fiebich BL, Cantarero I, Calzado MA, Bellido ML, Fernandez-Ruiz J, Appendino G, Guaza C, Muñoz E.
J Neuroimmune Pharmacol. 2012 Dec;7(4):1002-16. doi: 10.1007/s11481-012-9399-3. Epub 2012 Sep 14.
PMID: 22971837 [PubMed – in process]
Related citations


51. “The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB(1) and FAAH-independent mechanisms.”
Bosier B, Muccioli GG, Lambert DM.
Br J Pharmacol. 2012 Sep 12. doi: 10.1111/j.1476-5381.2012.02208.x. [Epub ahead of print]
PMID: 22970888 [PubMed – as supplied by publisher]
Related citations


52. Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.
Takeda S, Okajima S, Miyoshi H, Yoshida K, Okamoto Y, Okada T, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H.
Toxicol Lett. 2012 Nov 15;214(3):314-9. doi: 10.1016/j.toxlet.2012.08.029. Epub 2012 Sep 8.
PMID: 22963825 [PubMed – indexed for MEDLINE]
Related citations


53. Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis.
Podda G, Constantinescu CS.
Expert Opin Biol Ther. 2012 Nov;12(11):1517-31. doi: 10.1517/14712598.2012.721765. Epub 2012 Sep 7.
PMID: 22954177 [PubMed – in process]
Related citations


54. Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization.
Lacroix C, Saussereau E.
J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:85-95. doi: 10.1016/j.jchromb.2012.08.006. Epub 2012 Aug 13.
PMID: 22921635 [PubMed – indexed for MEDLINE]
Related citations


55. On-site test for cannabinoids in oral fluid.
Desrosiers NA, Lee D, Schwope DM, Milman G, Barnes AJ, Gorelick DA, Huestis MA.
Clin Chem. 2012 Oct;58(10):1418-25. Epub 2012 Aug 21.
PMID: 22912396 [PubMed – indexed for MEDLINE]
Related citations


56. Sativex long-term use: an open-label trial in patients with spasticity due to multiple sclerosis.
Serpell MG, Notcutt W, Collin C.
J Neurol. 2013 Jan;260(1):285-95. doi: 10.1007/s00415-012-6634-z. Epub 2012 Aug 10.
PMID: 22878432 [PubMed – in process]
Related citations


57. Cannabidiol treatment ameliorates ischemia/reperfusion renal injury in rats.
Fouad AA, Al-Mulhim AS, Jresat I.
Life Sci. 2012 Sep 17;91(7-8):284-92. doi: 10.1016/j.lfs.2012.07.030. Epub 2012 Aug 1.
PMID: 22877651 [PubMed – indexed for MEDLINE]
Related citations


58. Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT(1A) receptors in the dorsal raphe nucleus.
Katsidoni V, Anagnostou I, Panagis G.
Addict Biol. 2013 Mar;18(2):286-96. doi: 10.1111/j.1369-1600.2012.00483.x. Epub 2012 Aug 2.
PMID: 22862835 [PubMed – in process]
Related citations


59. Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB(1) and CB(2) Receptors.
Valdeolivas S, Satta V, Pertwee RG, Fernández-Ruiz J, Sagredo O.
ACS Chem Neurosci. 2012 May 16;3(5):400-6. doi: 10.1021/cn200114w. Epub 2012 Feb 9.
PMID: 22860209 [PubMed]
Related citations


60. Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice.
Li K, Feng JY, Li YY, Yuece B, Lin XH, Yu LY, Li YN, Feng YJ, Storr M.
Pancreas. 2013 Jan;42(1):123-9. doi: 10.1097/MPA.0b013e318259f6f0.
PMID: 22850623 [PubMed – in process]
Related citations


61. Towards the use of non-psychoactive cannabinoids for prostate cancer.
Pacher P.
Br J Pharmacol. 2013 Jan;168(1):76-8. doi: 10.1111/j.1476-5381.2012.02121.x.
PMID: 22849856 [PubMed – in process]
Related citations


62. siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration.
McHugh D, Wager-Miller J, Page J, Bradshaw HB.
J Mol Signal. 2012 Jul 26;7(1):10. doi: 10.1186/1750-2187-7-10.
PMID: 22834922 [PubMed] Free PMC Article
Related citations


63. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.
Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C, Klosterkötter J, Hellmich M, Koethe D.
Transl Psychiatry. 2012 Mar 20;2:e94. doi: 10.1038/tp.2012.15.
PMID: 22832859 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


64. The atypical cannabinoid o-1602: targets, actions, and the central nervous system.
Ashton JC.
Cent Nerv Syst Agents Med Chem. 2012 Sep;12(3):233-9.
PMID: 22831390 [PubMed – in process]
Related citations


65. Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview.
Esposito G, Filippis DD, Cirillo C, Iuvone T, Capoccia E, Scuderi C, Steardo A, Cuomo R, Steardo L.
Phytother Res. 2012 Jul 20. doi: 10.1002/ptr.4781. [Epub ahead of print]
PMID: 22815234 [PubMed – as supplied by publisher]
Related citations


66. CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells.
Arnold JC, Hone P, Holland ML, Allen JD.
Pharmacol Rep. 2012;64(3):751-7.
PMID: 22814029 [PubMed – indexed for MEDLINE] Free Article
Related citations


67. New biocomposites based on bioplastic flax fibers and biodegradable polymers.
Wróbel-Kwiatkowska M, Czemplik M, Kulma A, Zuk M, Kaczmar J, Dymińska L, Hanuza J, Ptak M, Szopa J.
Biotechnol Prog. 2012 Sep-Oct;28(5):1336-46. doi: 10.1002/btpr.1599. Epub 2012 Aug 17.
PMID: 22807200 [PubMed – indexed for MEDLINE]
Related citations


68. Simultaneous quantification of free and glucuronidated cannabinoids in human urine by liquid chromatography tandem mass spectrometry.
Scheidweiler KB, Desrosiers NA, Huestis MA.
Clin Chim Acta. 2012 Nov 20;413(23-24):1839-47. doi: 10.1016/j.cca.2012.06.034. Epub 2012 Jul 6.
PMID: 22771478 [PubMed – indexed for MEDLINE]
Related citations


69. Comment on: “Anxiogenic-like effects of chronic cannabidiol administration in rats” (Elbatsh MM, Assareh N, Marsden CA, Kendall DA, Psychopharmacology 2012).
Gururajan A.
Psychopharmacology (Berl). 2012 Aug;222(4):725-6; author reply 727. doi: 10.1007/s00213-012-2780-3. Epub 2012 Jul 4. No abstract available.
PMID: 22760485 [PubMed – indexed for MEDLINE]
Related citations


70. Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress.
Mecha M, Torrao AS, Mestre L, Carrillo-Salinas FJ, Mechoulam R, Guaza C.
Cell Death Dis. 2012 Jun 28;3:e331. doi: 10.1038/cddis.2012.71.
PMID: 22739983 [PubMed – in process] Free PMC Article
Related citations


71. Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
Schier AR, Ribeiro NP, Silva AC, Hallak JE, Crippa JA, Nardi AE, Zuardi AW.
Rev Bras Psiquiatr. 2012 Jun;34 Suppl 1:S104-10. Review. English, Portuguese.
PMID: 22729452 [PubMed – indexed for MEDLINE] Free Article
Related citations


72. Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report.
Vicente-Valor MI, Garcia-Llopis P, Mejia Andujar L, Antonino de la Camara G, García del Busto N, Lopez Tinoco MJ, Quintana Vergara B, Peiro Vilaplana C, Dominguez Moran JA, Sánchez Alcaraz A.
J Clin Pharm Ther. 2013 Feb;38(1):71-3. doi: 10.1111/j.1365-2710.2012.01365.x. Epub 2012 Jun 21.
PMID: 22726074 [PubMed – in process]
Related citations


73. A validated method for the analysis of cannabinoids in post-mortem blood using liquid-liquid extraction and two-dimensional gas chromatography-mass spectrometry.
Andrews R, Paterson S.
Forensic Sci Int. 2012 Oct 10;222(1-3):111-7. doi: 10.1016/j.forsciint.2012.05.007. Epub 2012 Jun 18.
PMID: 22717553 [PubMed – indexed for MEDLINE]
Related citations


74. A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation.
Zuardi AW, Crippa JA, Hallak JE, Bhattacharyya S, Atakan Z, Martin-Santos R, McGuire PK, Guimarães FS.
Curr Pharm Des. 2012;18(32):5131-40.
PMID: 22716160 [PubMed – in process]
Related citations


75. The endocannabinoid system and schizophrenia: integration of evidence.
Zamberletti E, Rubino T, Parolaro D.
Curr Pharm Des. 2012;18(32):4980-90.
PMID: 22716159 [PubMed – in process]
Related citations


76. Subjective and physiological effects of oromucosal sprays containing cannabinoids (nabiximols): potentials and limitations for psychosis research.
Schoedel KA, Harrison SJ.
Curr Pharm Des. 2012;18(32):5008-14.
PMID: 22716155 [PubMed – in process]
Related citations


77. Antipsychotic-like effects of cannabidiol and rimonabant: systematic review of animal and human studies.
Roser P, Haussleiter IS.
Curr Pharm Des. 2012;18(32):5141-55.
PMID: 22716153 [PubMed – in process]
Related citations


78. Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers.
Martin-Santos R, Crippa JA, Batalla A, Bhattacharyya S, Atakan Z, Borgwardt S, Allen P, Seal M, Langohr K, Farré M, Zuardi AW, McGuire PK.
Curr Pharm Des. 2012;18(32):4966-79.
PMID: 22716148 [PubMed – in process]
Related citations


79. Antipsychotic profile of cannabidiol and rimonabant in an animal model of emotional context processing in schizophrenia.
Levin R, Almeida V, Peres FF, Calzavara MB, da Silva ND, Suiama MA, Niigaki ST, Zuardi AW, Hallak JE, Crippa JA, Abílio VC.
Curr Pharm Des. 2012;18(32):4960-5.
PMID: 22716146 [PubMed – in process]
Related citations


80. Potential protective effects of cannabidiol on neuroanatomical alterations in cannabis users and psychosis: a critical review.
Hermann D, Schneider M.
Curr Pharm Des. 2012;18(32):4897-905.
PMID: 22716143 [PubMed – in process]
Related citations


81. Neural mechanisms for the cannabinoid modulation of cognition and affect in man: a critical review of neuroimaging studies.
Bhattacharyya S, Atakan Z, Martin-Santos R, Crippa JA, McGuire PK.
Curr Pharm Des. 2012;18(32):5045-54.
PMID: 22716136 [PubMed – in process]
Related citations


82. The yin and yang of cannabis-induced psychosis: the actions of Δ(9)-tetrahydrocannabinol and cannabidiol in rodent models of schizophrenia.
Arnold JC, Boucher AA, Karl T.
Curr Pharm Des. 2012;18(32):5113-30.
PMID: 22716133 [PubMed – in process]
Related citations


83. Cannabinoid-like anti-inflammatory compounds from flax fiber.
Styrczewska M, Kulma A, Ratajczak K, Amarowicz R, Szopa J.
Cell Mol Biol Lett. 2012 Sep;17(3):479-99. doi: 10.2478/s11658-012-0023-6. Epub 2012 Jun 13.
PMID: 22706678 [PubMed – indexed for MEDLINE]
Related citations


84. Cannabinoids for epilepsy.
Gloss D, Vickrey B.
Cochrane Database Syst Rev. 2012 Jun 13;6:CD009270. doi: 10.1002/14651858.CD009270.pub2. Review.
PMID: 22696383 [PubMed – indexed for MEDLINE]
Related citations


85. Sativex® in multiple sclerosis spasticity: a cost-effectiveness model.
Slof J, Gras A.
Expert Rev Pharmacoecon Outcomes Res. 2012 Aug;12(4):439-41. doi: 10.1586/erp.12.40. Epub 2012 Jun 8.
PMID: 22681512 [PubMed – indexed for MEDLINE]
Related citations


86. Is the cardiovascular system a therapeutic target for cannabidiol?
Stanley CP, Hind WH, O’Sullivan SE.
Br J Clin Pharmacol. 2013 Feb;75(2):313-22. doi: 10.1111/j.1365-2125.2012.04351.x.
PMID: 22670794 [PubMed – in process]
Related citations


87. Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function.
Pazos MR, Cinquina V, Gómez A, Layunta R, Santos M, Fernández-Ruiz J, Martínez-Orgado J.
Neuropharmacology. 2012 Oct;63(5):776-83. doi: 10.1016/j.neuropharm.2012.05.034. Epub 2012 May 30.
PMID: 22659086 [PubMed – indexed for MEDLINE]
Related citations


88. Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery.
Baranowska-Kuczko M, MacLean MR, Kozłowska H, Malinowska B.
Pharmacol Res. 2012 Sep;66(3):251-9. doi: 10.1016/j.phrs.2012.05.004. Epub 2012 May 22.
PMID: 22627170 [PubMed – indexed for MEDLINE]
Related citations


89. Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
Fernández-Ruiz J, Sagredo O, Pazos MR, García C, Pertwee R, Mechoulam R, Martínez-Orgado J.
Br J Clin Pharmacol. 2013 Feb;75(2):323-33. doi: 10.1111/j.1365-2125.2012.04341.x.
PMID: 22625422 [PubMed – in process]
Related citations


90. Cannabidiol inhibits angiogenesis by multiple mechanisms.
Solinas M, Massi P, Cantelmo AR, Cattaneo MG, Cammarota R, Bartolini D, Cinquina V, Valenti M, Vicentini LM, Noonan DM, Albini A, Parolaro D.
Br J Pharmacol. 2012 Nov;167(6):1218-31. doi: 10.1111/j.1476-5381.2012.02050.x.
PMID: 22624859 [PubMed – in process]
Related citations


91. First systematic evaluation of the potency of Cannabis sativa plants grown in Albania.
Bruci Z, Papoutsis I, Athanaselis S, Nikolaou P, Pazari E, Spiliopoulou C, Vyshka G.
Forensic Sci Int. 2012 Oct 10;222(1-3):40-6. doi: 10.1016/j.forsciint.2012.04.032. Epub 2012 May 18.
PMID: 22608266 [PubMed – indexed for MEDLINE]
Related citations


92. Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.
De Petrocellis L, Ligresti A, Schiano Moriello A, Iappelli M, Verde R, Stott CG, Cristino L, Orlando P, Di Marzo V.
Br J Pharmacol. 2013 Jan;168(1):79-102. doi: 10.1111/j.1476-5381.2012.02027.x.
PMID: 22594963 [PubMed – in process]
Related citations


93. Isomerization of cannabidiol and Δ9-tetrahydrocannabinol during positive electrospray ionization. In-source hydrogen/deuterium exchange experiments by flow injection hybrid quadrupole-time-of-flight mass spectrometry.
Broecker S, Pragst F.
Rapid Commun Mass Spectrom. 2012 Jun 30;26(12):1407-14. doi: 10.1002/rcm.6244.
PMID: 22592984 [PubMed – indexed for MEDLINE]
Related citations


94. Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.
Xiong W, Cui T, Cheng K, Yang F, Chen SR, Willenbring D, Guan Y, Pan HL, Ren K, Xu Y, Zhang L.
J Exp Med. 2012 Jun 4;209(6):1121-34. doi: 10.1084/jem.20120242. Epub 2012 May 14.
PMID: 22585736 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


95. Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow-enhancing effects of abnormal-cannabidiol.
Qiao Z, Kumar A, Kumar P, Song ZH.
Exp Eye Res. 2012 Jul;100:59-64. doi: 10.1016/j.exer.2012.05.001. Epub 2012 May 8.
PMID: 22580290 [PubMed – indexed for MEDLINE]
Related citations


96. Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: development, characterization and in vitro evaluation of their antitumoral efficacy.
Hernán Pérez de la Ossa D, Ligresti A, Gil-Alegre ME, Aberturas MR, Molpeceres J, Di Marzo V, Torres Suárez AI.
J Control Release. 2012 Aug 10;161(3):927-32. doi: 10.1016/j.jconrel.2012.05.003. Epub 2012 May 10.
PMID: 22580111 [PubMed – indexed for MEDLINE]
Related citations


97. Simultaneous analysis of several synthetic cannabinoids, THC, CBD and CBN, in hair by ultra-high performance liquid chromatography tandem mass spectrometry. Method validation and application to real samples.
Salomone A, Gerace E, D’Urso F, Di Corcia D, Vincenti M.
J Mass Spectrom. 2012 May;47(5):604-10. doi: 10.1002/jms.2988.
PMID: 22576873 [PubMed – indexed for MEDLINE]
Related citations


98. Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures.
Moldzio R, Pacher T, Krewenka C, Kranner B, Novak J, Duvigneau JC, Rausch WD.
Phytomedicine. 2012 Jun 15;19(8-9):819-24. doi: 10.1016/j.phymed.2012.04.002. Epub 2012 May 7.
PMID: 22571976 [PubMed – indexed for MEDLINE]
Related citations


99. A survey of the potency of Japanese illicit cannabis in fiscal year 2010.
Tsumura Y, Aoki R, Tokieda Y, Akutsu M, Kawase Y, Kataoka T, Takagi T, Mizuno T, Fukada M, Fujii H, Kurahashi K.
Forensic Sci Int. 2012 Sep 10;221(1-3):77-83. doi: 10.1016/j.forsciint.2012.04.005. Epub 2012 May 1.
PMID: 22554871 [PubMed – indexed for MEDLINE]
Related citations


100. On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment.
Stern CA, Gazarini L, Takahashi RN, Guimarães FS, Bertoglio LJ.
Neuropsychopharmacology. 2012 Aug;37(9):2132-42. doi: 10.1038/npp.2012.63. Epub 2012 May 2.
PMID: 22549120 [PubMed – in process]
Related citations


101. Cannabinol and cannabidiol exert opposing effects on rat feeding patterns.
Farrimond JA, Whalley BJ, Williams CM.
Psychopharmacology (Berl). 2012 Sep;223(1):117-29. doi: 10.1007/s00213-012-2697-x. Epub 2012 Apr 28.
PMID: 22543671 [PubMed – indexed for MEDLINE]
Related citations


102. Cannabidiol-induced apoptosis in murine microglial cells through lipid raft.
Wu HY, Goble K, Mecha M, Wang CC, Huang CH, Guaza C, Jan TR.
Glia. 2012 Jul;60(7):1182-90. doi: 10.1002/glia.22345. Epub 2012 Apr 25.
PMID: 22535572 [PubMed – indexed for MEDLINE]
Related citations


103. Cannabinoid stability in authentic oral fluid after controlled cannabis smoking.
Lee D, Milman G, Schwope DM, Barnes AJ, Gorelick DA, Huestis MA.
Clin Chem. 2012 Jul;58(7):1101-9. doi: 10.1373/clinchem.2012.184929. Epub 2012 Apr 24.
PMID: 22532594 [PubMed – indexed for MEDLINE]
Related citations


104. Evaluation of the safety and tolerability profile of Sativex: is it reassuring enough?
Wade D.
Expert Rev Neurother. 2012 Apr;12(4 Suppl):9-14. doi: 10.1586/ern.12.12. Review.
PMID: 22509986 [PubMed – indexed for MEDLINE]
Related citations


105. Clinical efficacy and effectiveness of Sativex, a combined cannabinoid medicine, in multiple sclerosis-related spasticity.
Oreja-Guevara C.
Expert Rev Neurother. 2012 Apr;12(4 Suppl):3-8. doi: 10.1586/ern.12.11. Review.
PMID: 22509985 [PubMed – indexed for MEDLINE]
Related citations


106. Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.
Jones NA, Glyn SE, Akiyama S, Hill TD, Hill AJ, Weston SE, Burnett MD, Yamasaki Y, Stephens GJ, Whalley BJ, Williams CM.
Seizure. 2012 Jun;21(5):344-52. doi: 10.1016/j.seizure.2012.03.001. Epub 2012 Apr 19.
PMID: 22520455 [PubMed – indexed for MEDLINE]
Related citations


107. Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice.
Long LE, Chesworth R, Huang XF, Wong A, Spiro A, McGregor IS, Arnold JC, Karl T.
PLoS One. 2012;7(4):e34129. doi: 10.1371/journal.pone.0034129. Epub 2012 Apr 3.
PMID: 22509273 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


108. Cannabidiol as potential anticancer drug.
Massi P, Solinas M, Cinquina V, Parolaro D.
Br J Clin Pharmacol. 2013 Feb;75(2):303-12. doi: 10.1111/j.1365-2125.2012.04298.x.
PMID: 22506672 [PubMed – in process]
Related citations


109. Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats.
Gururajan A, Taylor DA, Malone DT.
J Psychopharmacol. 2012 Oct;26(10):1317-32. doi: 10.1177/0269881112441865. Epub 2012 Apr 9.
PMID: 22495620 [PubMed – indexed for MEDLINE]
Related citations


110. Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial.
Portenoy RK, Ganae-Motan ED, Allende S, Yanagihara R, Shaiova L, Weinstein S, McQuade R, Wright S, Fallon MT.
J Pain. 2012 May;13(5):438-49. doi: 10.1016/j.jpain.2012.01.003. Epub 2012 Apr 5.
PMID: 22483680 [PubMed – indexed for MEDLINE]
Related citations


111. Chemiluminescence detection of cannabinoids and related compounds with acidic potassium permanganate.
Holland BJ, Francis PS, Li B, Tsuzuki T, Adcock JL, Barnett NW, Conlan XA.
Drug Test Anal. 2012 Jul-Aug;4(7-8):675-9. doi: 10.1002/dta.1328. Epub 2012 Mar 29.
PMID: 22461321 [PubMed – indexed for MEDLINE]
Related citations


112. The therapeutic potential of the endocannabinoid system for Alzheimer’s disease.
Karl T, Cheng D, Garner B, Arnold JC.
Expert Opin Ther Targets. 2012 Apr;16(4):407-20. doi: 10.1517/14728222.2012.671812. Epub 2012 Mar 27. Review.
PMID: 22448595 [PubMed – indexed for MEDLINE]
Related citations


113. New pain drugs in pipeline, but challenges to usage remain.
Brower V.
J Natl Cancer Inst. 2012 Apr 4;104(7):503-5. doi: 10.1093/jnci/djs199. Epub 2012 Mar 22. No abstract available.
PMID: 22440682 [PubMed – indexed for MEDLINE]
Related citations


114. [The potential use of cannabidiol in the therapy of metabolic syndrome].
Kleiner D, Ditrói K.
Orv Hetil. 2012 Apr 1;153(13):499-504. doi: 10.1556/OH.2012.29308. Review. Hungarian.
PMID: 22430005 [PubMed – indexed for MEDLINE] Free Article
Related citations


115. Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice.
Schicho R, Storr M.
Pharmacology. 2012;89(3-4):149-55. doi: 10.1159/000336871. Epub 2012 Mar 12.
PMID: 22414698 [PubMed – indexed for MEDLINE] Free Article
Related citations


116. Heat exposure of Cannabis sativa extracts affects the pharmacokinetic and metabolic profile in healthy male subjects.
Eichler M, Spinedi L, Unfer-Grauwiler S, Bodmer M, Surber C, Luedi M, Drewe J.
Planta Med. 2012 May;78(7):686-91. doi: 10.1055/s-0031-1298334. Epub 2012 Mar 12.
PMID: 22411724 [PubMed – indexed for MEDLINE]
Related citations


117. Blurred boundaries: the therapeutics and politics of medical marijuana.
Bostwick JM.
Mayo Clin Proc. 2012 Feb;87(2):172-86. doi: 10.1016/j.mayocp.2011.10.003. Review.
PMID: 22305029 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


118. Comparison of bulk and compound-specific δ13C isotope ratio analyses for the discrimination between cannabis samples.
Muccio Z, Wöckel C, An Y, Jackson GP.
J Forensic Sci. 2012 May;57(3):757-64. doi: 10.1111/j.1556-4029.2011.02046.x. Epub 2012 Jan 31.
PMID: 22292792 [PubMed]
Related citations


119. Production of identical retention times and mass spectra for {delta}9-tetrahydrocannabinol and cannabidiol following derivatization with trifluoracetic anhydride with 1,1,1,3,3,3-hexafluoroisopropanol*.
Andrews R, Paterson S.
J Anal Toxicol. 2012 Jan-Feb;36(1):61-5. doi: 10.1093/jat/bkr017.
PMID: 22290754 [PubMed – indexed for MEDLINE]
Related citations


120. Cannabinoids and metabolites in expectorated oral fluid following controlled smoked cannabis.
Milman G, Schwope DM, Gorelick DA, Huestis MA.
Clin Chim Acta. 2012 Apr 11;413(7-8):765-70. doi: 10.1016/j.cca.2012.01.011. Epub 2012 Jan 20.
PMID: 22285315 [PubMed – indexed for MEDLINE]
Related citations


121. Cannabinoids: novel medicines for the treatment of Huntington’s disease.
Sagredo O, Pazos MR, Valdeolivas S, Fernandez-Ruiz J.
Recent Pat CNS Drug Discov. 2012 Apr 1;7(1):41-8. Review.
PMID: 22280340 [PubMed – indexed for MEDLINE]
Related citations


122. Cannabinoid-related agents in the treatment of anxiety disorders: current knowledge and future perspectives.
Tambaro S, Bortolato M.
Recent Pat CNS Drug Discov. 2012 Apr 1;7(1):25-40. Review.
PMID: 22280339 [PubMed – indexed for MEDLINE]
Related citations


123. Cannabinoid disposition in oral fluid after controlled smoked cannabis.
Lee D, Schwope DM, Milman G, Barnes AJ, Gorelick DA, Huestis MA.
Clin Chem. 2012 Apr;58(4):748-56. doi: 10.1373/clinchem.2011.177881. Epub 2012 Jan 24.
PMID: 22273566 [PubMed – indexed for MEDLINE]
Related citations


124. Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature.
Crippa JA, Derenusson GN, Chagas MH, Atakan Z, Martín-Santos R, Zuardi AW, Hallak JE.
Harm Reduct J. 2012 Jan 25;9(1):7. doi: 10.1186/1477-7517-9-7.
PMID: 22273390 [PubMed] Free PMC Article
Related citations


125. Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor.
Ribeiro A, Ferraz-de-Paula V, Pinheiro ML, Vitoretti LB, Mariano-Souza DP, Quinteiro-Filho WM, Akamine AT, Almeida VI, Quevedo J, Dal-Pizzol F, Hallak JE, Zuardi AW, Crippa JA, Palermo-Neto J.
Eur J Pharmacol. 2012 Mar 5;678(1-3):78-85. doi: 10.1016/j.ejphar.2011.12.043. Epub 2012 Jan 12.
PMID: 22265864 [PubMed – indexed for MEDLINE]
Related citations


126. Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson’s disease.
Carroll CB, Zeissler ML, Hanemann CO, Zajicek JP.
Neuropathol Appl Neurobiol. 2012 Oct;38(6):535-47. doi: 10.1111/j.1365-2990.2011.01248.x.
PMID: 22236282 [PubMed – indexed for MEDLINE]
Related citations


127. Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.
Harvey BS, Ohlsson KS, Mååg JL, Musgrave IF, Smid SD.
Neurotoxicology. 2012 Jan;33(1):138-46. doi: 10.1016/j.neuro.2011.12.015. Epub 2012 Jan 3.
PMID: 22233683 [PubMed – indexed for MEDLINE]
Related citations


128. Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
Aviello G, Romano B, Borrelli F, Capasso R, Gallo L, Piscitelli F, Di Marzo V, Izzo AA.
J Mol Med (Berl). 2012 Aug;90(8):925-34. doi: 10.1007/s00109-011-0856-x. Epub 2012 Jan 10.
PMID: 22231745 [PubMed – indexed for MEDLINE]
Related citations


129. Induction of psychosis by Δ9-tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing.
Bhattacharyya S, Crippa JA, Allen P, Martin-Santos R, Borgwardt S, Fusar-Poli P, Rubia K, Kambeitz J, O’Carroll C, Seal ML, Giampietro V, Brammer M, Zuardi AW, Atakan Z, McGuire PK.
Arch Gen Psychiatry. 2012 Jan;69(1):27-36. doi: 10.1001/archgenpsychiatry.2011.161.
PMID: 22213786 [PubMed – indexed for MEDLINE]
Related citations


130. Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1.
Ramer R, Bublitz K, Freimuth N, Merkord J, Rohde H, Haustein M, Borchert P, Schmuhl E, Linnebacher M, Hinz B.
FASEB J. 2012 Apr;26(4):1535-48. doi: 10.1096/fj.11-198184. Epub 2011 Dec 23.
PMID: 22198381 [PubMed – indexed for MEDLINE]
Related citations


131. The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB(1)).
Grabiec U, Koch M, Kallendrusch S, Kraft R, Hill K, Merkwitz C, Ghadban C, Lutz B, Straiker A, Dehghani F.
Neuropharmacology. 2012 Mar;62(4):1797-807. doi: 10.1016/j.neuropharm.2011.11.023. Epub 2011 Dec 13.
PMID: 22186081 [PubMed – indexed for MEDLINE]
Related citations


132. Cannabidiol affects the expression of genes involved in zinc homeostasis in BV-2 microglial cells.
Juknat A, Rimmerman N, Levy R, Vogel Z, Kozela E.
Neurochem Int. 2012 Nov;61(6):923-30. doi: 10.1016/j.neuint.2011.12.002. Epub 2011 Dec 9.
PMID: 22178458 [PubMed – in process]
Related citations


133. Comparison in the in vitro inhibitory effects of major phytocannabinoids and polycyclic aromatic hydrocarbons contained in marijuana smoke on cytochrome P450 2C9 activity.
Yamaori S, Koeda K, Kushihara M, Hada Y, Yamamoto I, Watanabe K.
Drug Metab Pharmacokinet. 2012;27(3):294-300. Epub 2011 Dec 13.
PMID: 22166891 [PubMed – indexed for MEDLINE] Free Article
Related citations


134. Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement.
Esposito G, Scuderi C, Valenza M, Togna GI, Latina V, De Filippis D, Cipriano M, Carratù MR, Iuvone T, Steardo L.
PLoS One. 2011;6(12):e28668. doi: 10.1371/journal.pone.0028668. Epub 2011 Dec 5.
PMID: 22163051 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


135. Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.
De Filippis D, Esposito G, Cirillo C, Cipriano M, De Winter BY, Scuderi C, Sarnelli G, Cuomo R, Steardo L, De Man JG, Iuvone T.
PLoS One. 2011;6(12):e28159. doi: 10.1371/journal.pone.0028159. Epub 2011 Dec 6.
PMID: 22163000 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


136. The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications.
Horváth B, Mukhopadhyay P, Haskó G, Pacher P.
Am J Pathol. 2012 Feb;180(2):432-42. doi: 10.1016/j.ajpath.2011.11.003. Epub 2011 Dec 5. Review.
PMID: 22155112 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


137. Cannabinoid hyperemesis syndrome.
Galli JA, Sawaya RA, Friedenberg FK.
Curr Drug Abuse Rev. 2011 Dec;4(4):241-9. Review.
PMID: 22150623 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


138. Safety and side effects of cannabidiol, a Cannabis sativa constituent.
Bergamaschi MM, Queiroz RH, Zuardi AW, Crippa JA.
Curr Drug Saf. 2011 Sep 1;6(4):237-49. Review.
PMID: 22129319 [PubMed – indexed for MEDLINE]
Related citations


139. Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
Sreevalsan S, Joseph S, Jutooru I, Chadalapaka G, Safe SH.
Anticancer Res. 2011 Nov;31(11):3799-807.
PMID: 22110202 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


140. Effect of cannabidiol on human gingival fibroblast extracellular matrix metabolism: MMP production and activity, and production of fibronectin and transforming growth factor β.
Rawal SY, Dabbous MKh, Tipton DA.
J Periodontal Res. 2012 Jun;47(3):320-9. doi: 10.1111/j.1600-0765.2011.01435.x. Epub 2011 Nov 17.
PMID: 22092062 [PubMed – indexed for MEDLINE]
Related citations


141. Screening for Selective Ligands for GPR55 – Antagonists.
Heynen-Genel S, Dahl R, Shi S, Milan L, Hariharan S, Sergienko E, Hedrick M, Dad S, Stonich D, Su Y, Vicchiarelli M, Mangravita-Novo A, Smith LH, Chung TDY, Sharir H, Caron MG, Barak LS, Abood ME.
Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
PMID: 22091481 [PubMed] Books & Documents
Related citations


142. Anxiogenic-like effects of chronic cannabidiol administration in rats.
ElBatsh MM, Assareh N, Marsden CA, Kendall DA.
Psychopharmacology (Berl). 2012 May;221(2):239-47. doi: 10.1007/s00213-011-2566-z. Epub 2011 Nov 15.
PMID: 22083592 [PubMed – indexed for MEDLINE]
Related citations


143. [Cannabinoids for symptomatic therapy of multiple sclerosis].
Husseini L, Leussink VI, Warnke C, Hartung HP, Kieseier BC.
Nervenarzt. 2012 Jun;83(6):695-704. doi: 10.1007/s00115-011-3401-9. Review. German.
PMID: 22080198 [PubMed – indexed for MEDLINE]
Related citations


144. [Does cannabis use lead to schizophrenia?].
Heekeren K.
Praxis (Bern 1994). 2011 Nov 2;100(22):1361-7. doi: 10.1024/1661-8157/a000714. Review. German.
PMID: 22048912 [PubMed – indexed for MEDLINE]
Related citations


145. Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.
Marco EM, García-Gutiérrez MS, Bermúdez-Silva FJ, Moreira FA, Guimarães F, Manzanares J, Viveros MP.
Front Behav Neurosci. 2011;5:63. doi: 10.3389/fnbeh.2011.00063. Epub 2011 Oct 5.
PMID: 22007164 [PubMed] Free PMC Article
Related citations


146. The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus.
Cluny NL, Naylor RJ, Whittle BA, Javid FA.
Arch Pharm Res. 2011 Sep;34(9):1509-17. doi: 10.1007/s12272-011-0913-6. Epub 2011 Oct 6.
PMID: 21975813 [PubMed – indexed for MEDLINE]
Related citations


147. Interaction between cannabidiol (CBD) and ∆(9)-tetrahydrocannabinol (THC): influence of administration interval and dose ratio between the cannabinoids.
Zuardi AW, Hallak JE, Crippa JA.
Psychopharmacology (Berl). 2012 Jan;219(1):247-9. doi: 10.1007/s00213-011-2495-x. Epub 2011 Sep 21. No abstract available.
PMID: 21947314 [PubMed – indexed for MEDLINE]
Related citations


148. Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats.
Fouad AA, Jresat I.
Eur J Pharmacol. 2011 Nov 16;670(1):216-23. doi: 10.1016/j.ejphar.2011.08.048. Epub 2011 Sep 14.
PMID: 21930120 [PubMed – indexed for MEDLINE]
Related citations


149. Phytocannabinoids as novel therapeutic agents in CNS disorders.
Hill AJ, Williams CM, Whalley BJ, Stephens GJ.
Pharmacol Ther. 2012 Jan;133(1):79-97. doi: 10.1016/j.pharmthera.2011.09.002. Epub 2011 Sep 6. Review.
PMID: 21924288 [PubMed – indexed for MEDLINE]
Related citations


150. Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm.
Uribe-Mariño A, Francisco A, Castiblanco-Urbina MA, Twardowschy A, Salgado-Rohner CJ, Crippa JA, Hallak JE, Zuardi AW, Coimbra NC.
Neuropsychopharmacology. 2012 Jan;37(2):412-21. doi: 10.1038/npp.2011.188. Epub 2011 Sep 14.
PMID: 21918503 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


151. Endocannabinoid system dysfunction in mood and related disorders.
Ashton CH, Moore PB.
Acta Psychiatr Scand. 2011 Oct;124(4):250-61. doi: 10.1111/j.1600-0447.2011.01687.x. Epub 2011 Mar 9. Review.
PMID: 21916860 [PubMed – indexed for MEDLINE]
Related citations


152. Cannabidiol-treated rats exhibited higher motor score after cryogenic spinal cord injury.
Kwiatkoski M, Guimarães FS, Del-Bel E.
Neurotox Res. 2012 Apr;21(3):271-80. doi: 10.1007/s12640-011-9273-8. Epub 2011 Sep 14.
PMID: 21915768 [PubMed – indexed for MEDLINE]
Related citations


153. A placebo-controlled, parallel-group, randomized withdrawal study of subjects with symptoms of spasticity due to multiple sclerosis who are receiving long-term Sativex® (nabiximols).
Notcutt W, Langford R, Davies P, Ratcliffe S, Potts R.
Mult Scler. 2012 Feb;18(2):219-28. doi: 10.1177/1352458511419700. Epub 2011 Aug 30.
PMID: 21878454 [PubMed – indexed for MEDLINE]
Related citations


154. Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders.
Fagherazzi EV, Garcia VA, Maurmann N, Bervanger T, Halmenschlager LH, Busato SB, Hallak JE, Zuardi AW, Crippa JA, Schröder N.
Psychopharmacology (Berl). 2012 Feb;219(4):1133-40. doi: 10.1007/s00213-011-2449-3. Epub 2011 Aug 26.
PMID: 21870037 [PubMed – indexed for MEDLINE]
Related citations


155. Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats.
Hsiao YT, Yi PL, Li CL, Chang FC.
Neuropharmacology. 2012 Jan;62(1):373-84. doi: 10.1016/j.neuropharm.2011.08.013. Epub 2011 Aug 16.
PMID: 21867717 [PubMed – indexed for MEDLINE]
Related citations


156. Identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration.
Schwope DM, Karschner EL, Gorelick DA, Huestis MA.
Clin Chem. 2011 Oct;57(10):1406-14. doi: 10.1373/clinchem.2011.171777. Epub 2011 Aug 11.
PMID: 21836075 [PubMed – indexed for MEDLINE] Free Article
Related citations


157. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus.
Rock EM, Bolognini D, Limebeer CL, Cascio MG, Anavi-Goffer S, Fletcher PJ, Mechoulam R, Pertwee RG, Parker LA.
Br J Pharmacol. 2012 Apr;165(8):2620-34. doi: 10.1111/j.1476-5381.2011.01621.x.
PMID: 21827451 [PubMed – indexed for MEDLINE]
Related citations


158. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.
Yamaori S, Okamoto Y, Yamamoto I, Watanabe K.
Drug Metab Dispos. 2011 Nov;39(11):2049-56. doi: 10.1124/dmd.111.041384. Epub 2011 Aug 5.
PMID: 21821735 [PubMed – indexed for MEDLINE] Free Article
Related citations


159. Molecular analysis of genetic fidelity in Cannabis sativa L. plants grown from synthetic (encapsulated) seeds following in vitro storage.
Lata H, Chandra S, Techen N, Khan IA, ElSohly MA.
Biotechnol Lett. 2011 Dec;33(12):2503-8. doi: 10.1007/s10529-011-0712-7. Epub 2011 Jul 30.
PMID: 21805186 [PubMed – indexed for MEDLINE]
Related citations


160. Cannabidiol-2′,6′-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro.
Takeda S, Hirayama A, Urata S, Mano N, Fukagawa K, Imamura M, Irii A, Kitajima S, Masuyama T, Nomiyama M, Tatei S, Tomita S, Kudo T, Noguchi M, Yamaguchi Y, Okamoto Y, Amamoto T, Fukunishi Y, Watanabe K, Omiecinski CJ, Aramaki H.
Biol Pharm Bull. 2011;34(8):1252-6.
PMID: 21804214 [PubMed – indexed for MEDLINE] Free Article
Related citations


161. Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being.
Morgan CJ, Gardener C, Schafer G, Swan S, Demarchi C, Freeman TP, Warrington P, Rupasinghe I, Ramoutar A, Tan N, Wingham G, Lewis S, Curran HV.
Psychol Med. 2011 Jul 29:1-10. [Epub ahead of print]
PMID: 21798112 [PubMed – as supplied by publisher]
Related citations


162. Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour.
Deiana S, Watanabe A, Yamasaki Y, Amada N, Arthur M, Fleming S, Woodcock H, Dorward P, Pigliacampo B, Close S, Platt B, Riedel G.
Psychopharmacology (Berl). 2012 Feb;219(3):859-73. doi: 10.1007/s00213-011-2415-0. Epub 2011 Jul 28.
PMID: 21796370 [PubMed – indexed for MEDLINE]
Related citations


163. Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.
Granjeiro EM, Gomes FV, Guimarães FS, Corrêa FM, Resstel LB.
Pharmacol Biochem Behav. 2011 Oct;99(4):743-8. doi: 10.1016/j.pbb.2011.06.027. Epub 2011 Jul 12.
PMID: 21771609 [PubMed – indexed for MEDLINE]
Related citations


164. Nonpsychotropic cannabinoids, abnormal cannabidiol and canabigerol-dimethyl heptyl, act at novel cannabinoid receptors to reduce intraocular pressure.
Szczesniak AM, Maor Y, Robertson H, Hung O, Kelly ME.
J Ocul Pharmacol Ther. 2011 Oct;27(5):427-35. doi: 10.1089/jop.2011.0041. Epub 2011 Jul 19.
PMID: 21770780 [PubMed – indexed for MEDLINE]
Related citations


165. Cannabinoids in oral fluid following passive exposure to marijuana smoke.
Moore C, Coulter C, Uges D, Tuyay J, van der Linde S, van Leeuwen A, Garnier M, Orbita J Jr.
Forensic Sci Int. 2011 Oct 10;212(1-3):227-30. doi: 10.1016/j.forsciint.2011.06.019. Epub 2011 Jul 18.
PMID: 21763088 [PubMed – indexed for MEDLINE]
Related citations


166. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Russo EB.
Br J Pharmacol. 2011 Aug;163(7):1344-64. doi: 10.1111/j.1476-5381.2011.01238.x. Review.
PMID: 21749363 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


167. Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability.
Alhamoruni A, Wright KL, Larvin M, O’Sullivan SE.
Br J Pharmacol. 2012 Apr;165(8):2598-610. doi: 10.1111/j.1476-5381.2011.01589.x.
PMID: 21745190 [PubMed – indexed for MEDLINE]
Related citations


168. Cannabidiol prevents the development of cold and mechanical allodynia in paclitaxel-treated female C57Bl6 mice.
Ward SJ, Ramirez MD, Neelakantan H, Walker EA.
Anesth Analg. 2011 Oct;113(4):947-50. doi: 10.1213/ANE.0b013e3182283486. Epub 2011 Jul 7.
PMID: 21737705 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


169. Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography-tandem mass spectrometry.
Schwope DM, Scheidweiler KB, Huestis MA.
Anal Bioanal Chem. 2011 Sep;401(4):1273-83. doi: 10.1007/s00216-011-5197-7. Epub 2011 Jul 5.
PMID: 21727996 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


170. Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation.
De Petrocellis L, Orlando P, Moriello AS, Aviello G, Stott C, Izzo AA, Di Marzo V.
Acta Physiol (Oxf). 2012 Feb;204(2):255-66. doi: 10.1111/j.1748-1716.2011.02338.x. Epub 2011 Aug 12.
PMID: 21726418 [PubMed – indexed for MEDLINE]
Related citations


171. Evaluate symptomatic therapy in MS: can clinical trials be fine-tuned?
Solaro C.
Eur J Neurol. 2011 Sep;18(9):1113-4. doi: 10.1111/j.1468-1331.2011.03425.x. Epub 2011 Jul 5. No abstract available.
PMID: 21726356 [PubMed – indexed for MEDLINE]
Related citations


172. A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents.
Lin XH, Yuece B, Li YY, Feng YJ, Feng JY, Yu LY, Li K, Li YN, Storr M.
Neurogastroenterol Motil. 2011 Sep;23(9):862-e342. doi: 10.1111/j.1365-2982.2011.01742.x. Epub 2011 Jul 5.
PMID: 21726355 [PubMed – indexed for MEDLINE]
Related citations


173. Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.
Jiang R, Yamaori S, Takeda S, Yamamoto I, Watanabe K.
Life Sci. 2011 Aug 1;89(5-6):165-70. doi: 10.1016/j.lfs.2011.05.018. Epub 2011 Jun 16.
PMID: 21704641 [PubMed – indexed for MEDLINE]
Related citations


174. The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives.
Marco EM, Laviola G.
J Psychopharmacol. 2012 Jan;26(1):150-63. doi: 10.1177/0269881111408459. Epub 2011 Jun 21. Review.
PMID: 21693551 [PubMed – indexed for MEDLINE]
Related citations


175. The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55.
Schuelert N, McDougall JJ.
Neurosci Lett. 2011 Aug 1;500(1):72-6. doi: 10.1016/j.neulet.2011.06.004. Epub 2011 Jun 13.
PMID: 21683763 [PubMed – indexed for MEDLINE]
Related citations


176. Screening and quantitation of multiclass drugs of abuse and pharmaceuticals in hair by fast liquid chromatography electrospray time-of-flight mass spectrometry.
Domínguez-Romero JC, García-Reyes JF, Molina-Díaz A.
J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2034-42. doi: 10.1016/j.jchromb.2011.05.034. Epub 2011 May 30.
PMID: 21680266 [PubMed – indexed for MEDLINE]
Related citations


177. Oral fluid cannabinoids in chronic, daily Cannabis smokers during sustained, monitored abstinence.
Lee D, Milman G, Barnes AJ, Goodwin RS, Hirvonen J, Huestis MA.
Clin Chem. 2011 Aug;57(8):1127-36. doi: 10.1373/clinchem.2011.164822. Epub 2011 Jun 15.
PMID: 21677094 [PubMed – indexed for MEDLINE] Free Article
Related citations


178. Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington’s disease.
Sagredo O, Pazos MR, Satta V, Ramos JA, Pertwee RG, Fernández-Ruiz J.
J Neurosci Res. 2011 Sep;89(9):1509-18. doi: 10.1002/jnr.22682. Epub 2011 Jun 14.
PMID: 21674569 [PubMed – indexed for MEDLINE]
Related citations


179. A randomized, double-blind, placebo-controlled, crossover study to evaluate the subjective abuse potential and cognitive effects of nabiximols oromucosal spray in subjects with a history of recreational cannabis use.
Schoedel KA, Chen N, Hilliard A, White L, Stott C, Russo E, Wright S, Guy G, Romach MK, Sellers EM.
Hum Psychopharmacol. 2011 Apr;26(3):224-36. doi: 10.1002/hup.1196.
PMID: 21671456 [PubMed – indexed for MEDLINE]
Related citations


180. Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.
Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS.
Psychopharmacology (Berl). 2011 Nov;218(2):443-57. doi: 10.1007/s00213-011-2342-0. Epub 2011 Jun 11.
PMID: 21667074 [PubMed – indexed for MEDLINE]
Related citations


181. Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis.
Lim MP, Devi LA, Rozenfeld R.
Cell Death Dis. 2011 Jun 9;2:e170. doi: 10.1038/cddis.2011.52.
PMID: 21654828 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


182. Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs.
Lafuente H, Alvarez FJ, Pazos MR, Alvarez A, Rey-Santano MC, Mielgo V, Murgia-Esteve X, Hilario E, Martinez-Orgado J.
Pediatr Res. 2011 Sep;70(3):272-7. doi: 10.1038/pr.2011.497.
PMID: 21654550 [PubMed – indexed for MEDLINE]
Related citations


183. The role of phytochemicals in the treatment and prevention of dementia.
Howes MJ, Perry E.
Drugs Aging. 2011 Jun 1;28(6):439-68. doi: 10.2165/11591310-000000000-00000. Review.
PMID: 21639405 [PubMed – indexed for MEDLINE]
Related citations


184. Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration.
Milman G, Barnes AJ, Schwope DM, Schwilke EW, Goodwin RS, Kelly DL, Gorelick DA, Huestis MA.
Anal Bioanal Chem. 2011 Aug;401(2):599-607. doi: 10.1007/s00216-011-5066-4. Epub 2011 Jun 3.
PMID: 21637933 [PubMed – indexed for MEDLINE]
Related citations


185. Analysis of abuse drugs in urine using surfactant-assisted dispersive liquid-liquid microextraction.
Moradi M, Yamini Y, Baheri T.
J Sep Sci. 2011 Jul;34(14):1722-9. doi: 10.1002/jssc.201100132. Epub 2011 May 24.
PMID: 21608128 [PubMed – indexed for MEDLINE]
Related citations


186. Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.
McHugh D, Page J, Dunn E, Bradshaw HB.
Br J Pharmacol. 2012 Apr;165(8):2414-24. doi: 10.1111/j.1476-5381.2011.01497.x.
PMID: 21595653 [PubMed – indexed for MEDLINE]
Related citations


187. Cannabis with high cannabidiol content is associated with fewer psychotic experiences.
Schubart CD, Sommer IE, van Gastel WA, Goetgebuer RL, Kahn RS, Boks MP.
Schizophr Res. 2011 Aug;130(1-3):216-21. doi: 10.1016/j.schres.2011.04.017. Epub 2011 May 17.
PMID: 21592732 [PubMed – indexed for MEDLINE]
Related citations


188. Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy.
Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A.
Mol Cancer Ther. 2011 Jul;10(7):1161-72. doi: 10.1158/1535-7163.MCT-10-1100. Epub 2011 May 12.
PMID: 21566064 [PubMed – indexed for MEDLINE] Free Article
Related citations


189. Prospects for cannabinoid therapies in basal ganglia disorders.
Fernández-Ruiz J, Moreno-Martet M, Rodríguez-Cueto C, Palomo-Garo C, Gómez-Cañas M, Valdeolivas S, Guaza C, Romero J, Guzmán M, Mechoulam R, Ramos JA.
Br J Pharmacol. 2011 Aug;163(7):1365-78. doi: 10.1111/j.1476-5381.2011.01365.x. Review.
PMID: 21545415 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


190. Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells.
Juknat A, Pietr M, Kozela E, Rimmerman N, Levy R, Coppola G, Geschwind D, Vogel Z.
Br J Pharmacol. 2012 Apr;165(8):2512-28. doi: 10.1111/j.1476-5381.2011.01461.x.
PMID: 21542829 [PubMed – indexed for MEDLINE]
Related citations


191. Abuse potential and psychoactive effects of δ-9-tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine.
Robson P.
Expert Opin Drug Saf. 2011 Sep;10(5):675-85. doi: 10.1517/14740338.2011.575778. Epub 2011 May 4. Review.
PMID: 21542664 [PubMed – indexed for MEDLINE]
Related citations


192. The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells.
Rimmerman N, Juknat A, Kozela E, Levy R, Bradshaw HB, Vogel Z.
Cell Mol Neurobiol. 2011 Aug;31(6):921-30. doi: 10.1007/s10571-011-9692-3. Epub 2011 Apr 30.
PMID: 21533611 [PubMed – indexed for MEDLINE]
Related citations


193. Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa.
Ruhaak LR, Felth J, Karlsson PC, Rafter JJ, Verpoorte R, Bohlin L.
Biol Pharm Bull. 2011;34(5):774-8.
PMID: 21532172 [PubMed – indexed for MEDLINE] Free Article
Related citations


194. Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential.
Stadelmann AM, Juckel G, Arning L, Gallinat J, Epplen JT, Roser P.
Neurosci Lett. 2011 May 27;496(1):60-4. doi: 10.1016/j.neulet.2011.04.003. Epub 2011 Apr 12.
PMID: 21513772 [PubMed – indexed for MEDLINE]
Related citations


195. A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells.
Chiba T, Ueno S, Obara Y, Nakahata N.
J Pharm Pharmacol. 2011 May;63(5):636-47. doi: 10.1111/j.2042-7158.2011.01250.x. Epub 2011 Mar 28.
PMID: 21492165 [PubMed – indexed for MEDLINE]
Related citations


196. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes.
Di Marzo V, Piscitelli F, Mechoulam R.
Handb Exp Pharmacol. 2011;(203):75-104. doi: 10.1007/978-3-642-17214-4_4. Review.
PMID: 21484568 [PubMed – indexed for MEDLINE]
Related citations


197. Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol.
Hegde VL, Nagarkatti PS, Nagarkatti M.
PLoS One. 2011 Apr 1;6(4):e18281. doi: 10.1371/journal.pone.0018281.
PMID: 21483776 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


198. Psychotropic and nonpsychotropic cannabis derivatives inhibit human 5-HT(3A) receptors through a receptor desensitization-dependent mechanism.
Xiong W, Koo BN, Morton R, Zhang L.
Neuroscience. 2011 Jun 16;184:28-37. doi: 10.1016/j.neuroscience.2011.03.066. Epub 2011 Apr 6.
PMID: 21477640 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations


199. Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia.
Gururajan A, Taylor DA, Malone DT.
Behav Brain Res. 2011 Sep 23;222(2):299-308. doi: 10.1016/j.bbr.2011.03.053. Epub 2011 Mar 31.
PMID: 21458498 [PubMed – indexed for MEDLINE]
Related citations


200. THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis.
Sastre-Garriga J, Vila C, Clissold S, Montalban X.
Expert Rev Neurother. 2011 May;11(5):627-37. doi: 10.1586/ern.11.47. Epub 2011 Apr 1. Review.
PMID: 21456949 [PubMed – indexed for MEDLINE]
Related citations

CBD and Cancer





Tumor Studies:



Clinical Trials:



Contact Us

We're not around right now. But you can send us an email and we'll get back to you, asap.

Not readable? Change text.

Start typing and press Enter to search